Keratin pearl is a form of keratinized structure, frequently visible at low-grade SCC and rarely observed at high-grade SCC . This feature is more clearly noticeable at low magnification images (25x, 40x).
Will keratin pearls go away on their own?
Keratin plugs can resolve on their own without treatment, but they can also be persistent and recur. They aren't contagious, and they aren't considered to be major medical concerns. If you're looking to get rid of stubborn keratin plugs, talk to your dermatologist about the following treatment options.
What causes keratin pearls to form?
When there is lack of cohesion among the epithelial cells due to malignant changes, the cells get arranged in a concentric manner. As the fate of a squamous cell is to form keratin, these cells lay down keratin in a concentric manner and then appear as keratin pearls which are known as malignant keratin pearls.
What cancers have keratin pearls?
For squamous cell carcinoma such as ESCC, keratin pearls (KP) is one of the most distinctive pathological structures. KP are formed by local squamous epithelium accumulation , which is easily recognized under a microscope  and is considered a marker of well-differentiated squamous cell carcinoma .
How common are keratin pearls?
The presence of extensive squamous metaplasia and numerous keratin pearls is mostly uncommon in the microscopic study and can signify a potential pitfall in the histopathological diagnosis Pleomorphic adenoma can show the presence of squamous metaplasia with keratin pearls as a rare finding and is encountered most
Can you remove keratin pearls at home?
These keratin-filled plugs may go away on their own with time and with the use of lifestyle remedies. Never pick at keratin plugs, as this will make them irritated. If you fail to see results at home, see your dermatologist. They can evaluate your condition and may recommend professional treatments.