When you have a migraine, your body releases substances called neurotransmitters and molecules that are associated with pain. Botulinum toxin interferes with the transmission of these substances, typically where the nerves and muscles meet.
What is the downside of Botox for migraines?
The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms, including loss of strength and all-over muscle weakness; double vision; blurred vision; drooping eyelids; hoarseness or change or loss of voice; trouble saying words clearly; loss of bladder control; trouble
What is the mechanism of action of Botox for migraines?
How does Botox work to treat migraine? The mechanism by which Botox works to treat migraine is complex. It is thought to function by reducing the release of inflammatory and excitatory neurotransmitters and proteins.
What is the success rate of Botox for migraines?
If you have 20 days per month, your 50% response would be 10 days per month (not zero). In studies nearly 50% of patients achieved this goal after 6 months of treatment (2 sets of injections). Some people improve more than others (responders). 23% of patients in the studies improved by 75% (super responders).
Will Botox for migraines change my face?
4. You May Look a Bit Different. Many people are drawn to Botox for the perceived cosmetic benefit, but the Botox for migraines injection sites are different from those used for cosmetic purposes. So you can't count on looking like a movie star if your goal is migraine prevention.
How many units of Botox is normal for migraines?
Bottom Line. The recommended total dose of Botox (onabotulinumtoxinA) for chronic migraine prevention is 155 Units administered intramuscularly (into the muscle). This is given as 0.1 mL (5 Units) injections divided across 7 specific head and neck muscle areas, for a total of 31 individual injections per session.